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ENGLISH · EVIDENCE OVERVIEW

Ostarine / Enobosarm
evidence profile

Understand this molecule

What is Ostarine / Enobosarm?

Ostarine, also called enobosarm or MK-2866, is an investigational SARM acting on androgen hormone receptors.

How does it work?

Binds androgen receptors to study tissue effects. Selective action does not mean muscle-only action or no effects elsewhere.

What is it used or studied for?

Trials in selected older adults and people with cancer reported changes in lean body mass: body mass excluding fat.

Status in the reviewed information

FDA stated that no SARM was approved in the reviewed information. Exact products in Thailand, the EU and UK had not been verified.

Original review: · not a fresh status check today

What should I keep in mind?

Body-mass changes do not establish strength, bodybuilding benefit or long-term safety. MK-2866 is not MK-677.

Read the evidence and research in detail ↓

Nonsteroidal selective androgen receptor modulator candidate. This is a concise English overview, not a full translation. Read the evidence boundaries and original sources below; the detailed study and risk discussion remains available in Thai.

What do Class, Grade and Risk mean?

Ostarine / Enobosarm: conceptual scientific illustration for Clinical / Endocrine Pharmacology
VISUAL GUIDE · Ostarine / Enobosarm

Clinical / Endocrine Pharmacology

Category-level conceptual illustration, not a map of this molecule's receptor targets. It is not a treatment outcome and does not establish efficacy or safety.

QUICK ANSWER · AEO / GEO

Ostarine, enobosarm, GTx-024 and MK-2866 refer to the same investigational SARM candidate in the reviewed literature. Controlled trials reported lean-body-mass signals in selected older adults and cancer populations, but do not establish bodybuilding benefit, long-term safety or product approval. FDA states that no SARM is approved and warns of serious harms. Online naming does not establish identity or amount, and WADA 2026 prohibits enobosarm at all times.

01

ENTITY FACTS

What should readers identify first?

MOLECULEOstarine / Enobosarm
PHARMACOLOGYNonsteroidal selective androgen receptor modulator candidate
PRIMECORE CLASSB
EVIDENCE GRADEB
RESEARCH TOPICClinical / Endocrine Pharmacology
LAST REVIEWED2026-09-01

What remains unknown?

Insufficient data in the current dataset

What limits these conclusions?

  • Human trial signal ≠ approval ≠ bodybuilding evidence ≠ verified online product; Ostarine/MK-2866 ≠ MK-677

This overview does not replace the detailed adverse-event and product-specific risk discussion in the complete Thai profile or the original sources.

02

EVIDENCE BOUNDARY

What this overview does not establish

  • An evidence grade does not rank this molecule against another treatment.
  • A molecule name does not establish the identity, purity or regulatory status of a product.
  • Animal, cell or biomarker findings do not automatically establish human clinical benefit.
  • Approval in one country or indication does not transfer globally.

Where can I check the evidence?

Original sources from the same evidence record used by Compare. Read each source's population, methods, limitations and date; a citation is not product endorsement.

  1. FDA · Bodybuilding products and SARM safety warning · 2025
  2. FDA · Andarine and ostarine product recall
  3. WADA · 2026 Prohibited List
  4. Healthy older adults Phase 2 · PMID 22031847
  5. Cancer muscle-wasting Phase 2 · PMID 23499390
03

FAQ · ANSWER ENGINE

Frequently asked questions

What is Ostarine / Enobosarm?

Ostarine / Enobosarm is described pharmacologically as Nonsteroidal selective androgen receptor modulator candidate. Ostarine, enobosarm, GTx-024 and MK-2866 refer to the same investigational SARM candidate in the reviewed literature. Controlled trials reported lean-body-mass signals in selected older adults and cancer populations, but do not establish bodybuilding benefit, long-term safety or product approval. FDA states that no SARM is approved and warns of serious harms. Online naming does not establish identity or amount, and WADA 2026 prohibits enobosarm at all times.

Does Ostarine / Enobosarm have strong evidence?

PrimeCoreBio records Evidence Grade B. This grade describes evidence strength, not comparative effectiveness or suitability for an individual.

Is Ostarine / Enobosarm approved everywhere?

No global conclusion should be inferred. PrimeCore Class B must be read with the exact product, country and indication on the source-rich profile.

Medical Disclaimer

Educational information only. This page does not provide diagnosis, treatment, prescribing, dosage, injection instructions or individual medical advice.

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